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Changes in Weight Affect Human Body Drastically

London, Jan 20 (Prensa Latina) The human body undergoes drastic changes in the periods of weight gain and loss, even if they are mild, a study published in the journal Cell Systems reported.
According to the authors, even with a gain of 2.5 kilograms, the organism experiences various alterations at the molecular level.

'Bacterial populations are modified, immune responses and inflammation are exacerbated and the molecular pathways associated with heart disease are activated,' the study explained.

Developed by the Stanford University School of Medicine, the study included 23 participants, of whom 13 were insulin resistant and 10 were sensitive to that component.

Initially, the team found that molecular markers of inflammation were only found in the bloodstream of insulin-resistant patients.

Subsequently, the subjects received a diet high in calories and in one month they increased their weight by 2.5 kilograms.

The doctors found that the markers of inflammation rose in all people, but in those insulin-sensitive, the microbial population known to protect against diabetes increased significantly. But the most notable change was a change in gene expression associated with an increased risk of developing a type of heart failure in which the heart cannot pump blood efficiently to the rest of the body, experts said.

When the participants in the study lost weight, most of the bodily systems returned to their original state, but a small subset of changes related to weight gain and the production of proteins and molecules did persist.


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